Motif ID: DMAP1_NCOR{1,2}_SMARC.p2

Z-value: 1.356


Transcription factors associated with DMAP1_NCOR{1,2}_SMARC.p2:

Gene SymbolEntrez IDGene Name
DMAP1 55929 DNA methyltransferase 1 associated protein 1
NCOR1 9611 nuclear receptor co-repressor 1
NCOR2 9612 nuclear receptor co-repressor 2
SMARCA1 6594 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SMARCA5 8467 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMARCC2 6601 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
NCOR1chr17_-_16097882-0.801.6e-06Click!
SMARCA5chr4_+_144434555-0.793.1e-06Click!
SMARCC2chr12_-_56583244-0.769.7e-06Click!
SMARCA1chrX_-_128657381-0.701.1e-04Click!
DMAP1chr1_+_44679111-0.096.6e-01Click!
NCOR2chr12_-_125052009-0.048.5e-01Click!


Activity profile for motif DMAP1_NCOR{1,2}_SMARC.p2.

activity profile for motif DMAP1_NCOR{1,2}_SMARC.p2


Sorted Z-values histogram for motif DMAP1_NCOR{1,2}_SMARC.p2

Sorted Z-values for motif DMAP1_NCOR{1,2}_SMARC.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of DMAP1_NCOR{1,2}_SMARC.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_101185195 14.529 NM_001078
NM_001199834
NM_080682
VCAM1


vascular cell adhesion molecule 1


chr1_-_150738232 7.468 CTSS
cathepsin S
chr15_+_89182038 7.381 NM_002201
ISG20
interferon stimulated exonuclease gene 20kDa
chr17_+_6659356 6.554 XAF1
XIAP associated factor 1
chr1_-_150738255 6.325 CTSS
cathepsin S
chr1_-_150738292 6.168 NM_001199739
NM_004079
CTSS

cathepsin S

chr17_+_6659155 5.608 NM_017523
NM_199139
XAF1

XIAP associated factor 1

chr7_-_115670774 5.435 TFEC
transcription factor EC
chr7_-_92777657 5.195 NM_152703
SAMD9L
sterile alpha motif domain containing 9-like
chr10_+_91092238 5.191 NM_001031683
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr10_+_91152321 5.150 NM_001548
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr17_-_34207308 5.046 NM_002985
CCL5
chemokine (C-C motif) ligand 5
chr17_-_40264687 4.744 NM_024119
DHX58
DEXH (Asp-Glu-X-His) box polypeptide 58
chr8_+_17396285 4.559 NM_001164771
NM_003046
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr7_-_115670828 4.511 NM_001018058
NM_012252
TFEC

transcription factor EC

chr9_+_74920329 4.006


chr3_+_122283139 3.905 NM_138287
DTX3L
deltex 3-like (Drosophila)
chr4_-_169239816 3.744 NM_017631
DDX60
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr6_+_29691116 3.472 NM_001098478
NM_001098479
NM_018950
HLA-F


major histocompatibility complex, class I, F


chr11_-_104905849 3.466 CASP1
caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
3.88 5.19e-03 GO:0034340 response to type I interferon
3.70 2.06e-02 GO:0060337 type I interferon-mediated signaling pathway
3.70 2.06e-02 GO:0071357 cellular response to type I interferon
2.41 2.41e-02 GO:0019221 cytokine-mediated signaling pathway
2.11 9.65e-09 GO:0006955 immune response
2.11 2.21e-02 GO:0034097 response to cytokine stimulus
2.09 3.22e-03 GO:0045087 innate immune response
1.70 7.19e-06 GO:0002376 immune system process
1.67 2.65e-02 GO:2000026 regulation of multicellular organismal development
1.63 2.85e-02 GO:0006952 defense response
1.56 8.10e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.36 1.50e-02 GO:0048519 negative regulation of biological process
1.20 1.66e-04 GO:0050789 regulation of biological process
1.19 2.61e-03 GO:0050794 regulation of cellular process
1.17 1.29e-03 GO:0065007 biological regulation

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
2.04 7.23e-03 GO:0016563 transcription activator activity
1.71 3.39e-03 GO:0043565 sequence-specific DNA binding
1.18 1.62e-04 GO:0005515 protein binding